Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138228 | 0.93 | LMNA (0.37) | IRAK4L3MBTL1ALDH1A1LMNARAB9A | |
| SCHEMBL18138300 | 0.89 | PRMT1 (0.35) | L3MBTL1ALDH1A1HTTLMNAPRMT1 | |
| SCHEMBL18138302 | 0.88 | MMP1 (0.34) | ALDH1A1PRMT1GSTP1GSTM2BRD4 | |
| SCHEMBL18138287 | 0.88 | DUT (0.34) | L3MBTL1ALDH1A1RAB9APRMT1GSTP1 | |
| SCHEMBL18138351 | 0.86 | PRMT1 (0.36) | L3MBTL1ALDH1A1PRMT1GSTP1GSTM2 | |
| SCHEMBL18138301 | 0.86 | ALDH1A1 (0.35) | IRAK4L3MBTL1ALDH1A1LMNAPRMT1 | |
| SCHEMBL18131207 | 0.85 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1HTTLMNARAB9A | |
| SCHEMBL18138283 | 0.83 | PRMT1 (0.34) | IRAK4L3MBTL1ALDH1A1PRMT1GSTP1 | |
| SCHEMBL18131174 | 0.83 | MMP1 (0.35) | L3MBTL1ALDH1A1PRMT1GSTP1GSTM2 | |
| SCHEMBL18138350 | 0.83 | GSTP1 (0.33) | L3MBTL1ALDH1A1RAB9APRMT1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |