Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138301 | 0.94 | ALDH1A1 (0.35) | PRMT1IRAK4MAPK14L3MBTL1ALDH1A1 | |
| SCHEMBL18138351 | 0.87 | PRMT1 (0.36) | PRMT1MAPK14L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18138228 | 0.85 | LMNA (0.37) | PRMT1IRAK4L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18138300 | 0.85 | PRMT1 (0.35) | PRMT1MAPK14L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18131172 | 0.84 | PRMT1 (0.36) | PRMT1L3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL18131254 | 0.83 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18138290 | 0.83 | IRAK4 (0.35) | PRMT1IRAK4L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21753654 | 0.82 | L3MBTL1 (0.42) | PRMT1L3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL18138350 | 0.82 | GSTP1 (0.33) | PRMT1MAPK14L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL18131174 | 0.82 | MMP1 (0.35) | PRMT1L3MBTL1ALDH1A1GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164754-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-10-13 | — | — | WO | disclosed |