Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | SNCA | P37840 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755917 | 0.85 | CYP1A2 (0.34) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL10948979 | 0.67 | CYP1A2 (0.36) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL19928616 | 0.67 | ALDH1A1 (0.42) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL4495310 | 0.67 | CYP1A2 (0.44) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL28092263 | 0.63 | CYP1A2 (0.38) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL14377497 | 0.62 | ALDH1A1 (0.45) | ALDH1A1CYP1A2LMNAMAPTALOX15 | |
| SCHEMBL3186206 | 0.61 | ALDH1A1 (0.44) | ALDH1A1CYP1A2LMNAMAPTALOX15 | |
| SCHEMBL1659293 | 0.61 | CYP1A2 (0.44) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL19167425 | 0.61 | CYP1A2 (0.40) | ALDH1A1PTGS1CYP1A2LMNADRD3 | |
| SCHEMBL4678663 | 0.61 | CYP1A2 (0.40) | ALDH1A1PTGS1CYP1A2LMNADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11253489-B2 | Visual cycle modulators | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-02-22 | — | — | US | disclosed |
| US-20200060996-A1 | VISUAL CYCLE MODULATORS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200060996-A1 | VISUAL CYCLE MODULATORS | ALDH1A2, UACA, NR2E3 | ALDH1A1 1392/4885PTGS1 614/4885CYP1A2 3563/4885 |
| US-11253489-B2 | Visual cycle modulators | ALDH1A2, UACA, NR2E3 | ALDH1A1 1392/4885PTGS1 614/4885CYP1A2 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.