SCHEMBL217560

SCHEMBL217560

[CH2]c1c(OC)cccc1OC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA12 O43570 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA4 P22748 1/20 0.58
ALDH1A1 P00352 3/20 0.50
TP53 P04637 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
HSD17B10 Q99714 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28179421 0.97 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL4836485 0.85 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL10979658 0.84 SMN1; SMN2 (0.45) CA1CA2CA7CA9CA12
SCHEMBL4844534 0.84 NPSR1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL3160095 0.83 MAPT (0.64) CA1CA2CA7CA9CA12
SCHEMBL27563491 0.83 ALDH1A1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL687479 0.83 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL693558 0.83 NFE2L2 (0.47) CA1CA2CA7CA9CA12
SCHEMBL25372302 0.78 AR (0.43) CA1CA2CA7CA9CA12
SCHEMBL8478686 0.78 PDCD1 (0.46) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380998-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF Research Foundation Of The City University Of New York (US) 2024-06-12 EP claimed
CN-116874457-A Coumarin derivative containing acylhydrazone sulfoxide and synthetic method and application thereof 中国热带农业科学院环境与植物保护研究所 2023-10-13 CN claimed
WO-2023014875-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2023-02-09 WO claimed
EP-3560937-B1 METHODS OF PREPARING 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS AND DIAGNOSTIC METHODS THEREWITH CANCER TARGETED TECH LLC (US) 2022-12-28 EP claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-110627831-A Bibiaryl acetal phosphines, their preparation and use in coupling reactions 东莞市均成高新材料有限公司 2019-12-31 CN claimed
EP-3560937-A1 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS Cancer Targeted Technology LLC (US) 2019-10-30 EP claimed
EP-2970345-B1 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS CANCER TARGETED TECH LLC (US) 2019-06-19 EP claimed
US-10316026-B2 Method for removing dimethoxybenzyl group DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-06-11 US claimed
EP-3068405-B1 PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS GILEAD SCIENCES INC (US) 2019-05-01 EP claimed
EP-0815087-B1 TRISUBSTITUTED PHENYL DERIVATIVES NOVARTIS AG (CH) 2001-11-14 EP claimed
WO-2001040193-A1 METHOD FOR THE SYNTHESIS OF PYRAZOLINES CHEMRX ADVANCED TECHNOLOGIES, INC. (US) 2001-06-07 WO claimed
WO-2001000594-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-01-04 WO claimed
US-6043227-A C11 carbamates of macrolide antibacterials PFIZER INC. (US) 2000-03-28 US claimed
EP-0984019-A1 C11 carbamates of macrolide antibacterials Pfizer Products Inc. (US) 2000-03-08 EP claimed
CN-1183774-A Trisubstd phenyl derivs CIBA GEIGY AG (CH) 1998-06-03 CN claimed
EP-0815087-A1 TRISUBSTITUTED PHENYL DERIVATIVES Novartis AG (CH) 1998-01-07 EP claimed
WO-1996028430-A1 TRISUBSTITUTED PHENYL DERIVATIVES NOVARTIS AG (CH) 1996-09-19 WO claimed
US-5478959-A Method for preparing 1,2-dithiins and precursors of 1,2-dithiins THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1995-12-26 US claimed
US-4129735-A MULTISTAGE FROM AN OXAMIC ACID ESTER AND PHOSPHORUS PENTACHLORIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10316026-B2 Method for removing dimethoxybenzyl group DDT, ALKBH5, DDO CA1 2756/4885CA2 3283/4885CA7 1152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.