Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829273 | 0.79 | IDO1 (0.57) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL17820 | 0.79 | IDO1 (0.57) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL217560 | 0.78 | CA1 (0.58) | LMNAKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL10563090 | 0.78 | APOBEC3G (0.44) | PDCD1CD274LMNAKDM4ETP53 | |
| SCHEMBL13486908 | 0.78 | MEN1 (0.49) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL95873 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP3A4MAPK1CA12 | |
| SCHEMBL828720 | 0.78 | IDO1 (0.62) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL1029593 | 0.78 | PDE4A (0.45) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL4122863 | 0.78 | PDCD1 (0.51) | PDCD1CD274PDE4APDE4BPDE4C | |
| SCHEMBL27666615 | 0.77 | TAAR1 (0.43) | IDO1ALOX5PTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |