SCHEMBL21756029

SCHEMBL21756029

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)oc4c(-c6ccc7c8ccccc8c8ccccc8c7c6)cccc45)n3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
PRKDC P78527 8/20 0.42
GGPS1 O95749 1/20 0.38
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
MAPK1 P28482 1/20 0.35
NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26701631 0.99 ALOX5 (0.47) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL21756041 0.97 ALOX5 (0.48) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL25632795 0.96 ALOX5 (0.43) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL23623770 0.96 ALOX5 (0.49) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL24216510 0.96 ALOX5 (0.49) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL21756015 0.96 ALOX5 (0.49) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL24216270 0.95 ALOX5 (0.40) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL24169356 0.94 ALOX5 (0.53) ALOX5PRKDCGGPS1PIM1CSNK2A2
SCHEMBL21755967 0.94 ALOX5 (0.53) ALOX5PRKDCGGPS1MMP12MMP13
SCHEMBL24169781 0.94 ALOX5 (0.53) ALOX5PRKDCGGPS1PIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
WO-2022025714-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2022-02-03 WO disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
US-20210280800-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-09-09 US disclosed
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210280800-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, AOX1, CYBA ALOX5 497/4885PRKDC 4094/4885GGPS1 214/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 ALOX5 1552/4885PRKDC 3767/4885GGPS1 1923/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 ALOX5 1931/4885PRKDC 3471/4885GGPS1 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.