SCHEMBL21756077

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21651117	0.89	LMNA (0.43)	GAAMGAMSIMGAM2MCL1
	SCHEMBL26254443	0.87	GAA (0.49)	GAAMGAMSIMGAM2MCL1
	SCHEMBL17037793	0.83	CA9 (0.54)	MCL1BCL2ALDH1A1HSD17B10KMT2A
	SCHEMBL22375221	0.82	HSD17B10 (0.50)	ALDH1A1TSHRHSD17B10CYP3A4TDP1
	SCHEMBL21668964	0.81	CA9 (0.50)	GAAALDH1A1TSHRHSD17B10CYP3A4
	SCHEMBL24264582	0.80	HSD17B10 (0.48)	ALDH1A1TSHRHSD17B10CYP3A4TDP1
	SCHEMBL31577197	0.80	NPC1 (0.42)	ALDH1A1TSHRHSD17B10CYP3A4TDP1
	SCHEMBL31716139	0.79	CA9 (0.48)	MCL1BCL2ALDH1A1HSD17B10KMT2A
	SCHEMBL21658955	0.79	GAA (0.44)	GAAMGAMSIMGAM2MCL1
	SCHEMBL22737967	0.78	HSD17B10 (0.50)	ALDH1A1TSHRHSD17B10CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.