SCHEMBL21651117

SCHEMBL21651117

Oc1cc(Cl)ccc1-c1ccc(Br)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
GAA P10253 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 3/20 0.42
HTT P42858 3/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
HSP90AA1 P07900 1/20 0.40
NMUR2 Q9GZQ4 1/20 0.39
FLT1 P17948 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21658955 0.89 GAA (0.44) LMNAKMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL21756077 0.89 GAA (0.43) LMNAKMT2AALDH1A1SMN1; SMN2GAA
SCHEMBL22737967 0.86 HSD17B10 (0.50) LMNAKMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL27164738 0.86 BCL2 (0.45) LMNAKMT2AALDH1A1SMN1; SMN2NPC1
SCHEMBL22375221 0.82 HSD17B10 (0.50) LMNAKMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL21638095 0.81 CA3 (0.50) LMNAKMT2AALDH1A1SMN1; SMN2NPC1
SCHEMBL24264582 0.80 HSD17B10 (0.48) LMNAKMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL31577197 0.80 NPC1 (0.42) LMNAALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL14520998 0.79 DGAT1 (0.46) LMNAALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL31310573 0.79 DGAT1 (0.46) LMNAALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
EP-4270509-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
EP-3770157-B1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
US-20210388001-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG ELECTRONICS INC. (KR) 2021-12-16 US disclosed
US-20210320260-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed
US-20210280800-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-09-09 US disclosed
US-20210184131-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-06-17 US disclosed
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-05-13 US disclosed
EP-3808744-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2021-04-21 EP disclosed
EP-3778594-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2021-02-17 EP disclosed
EP-3770157-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME LG CHEM, LTD. (KR) 2021-01-27 EP disclosed
WO-2020085740-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-04-30 WO disclosed
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed
WO-2020022860-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same ARNT, AHR, DRD1 LMNA 4737/4885KMT2A 2412/4885ALDH1A1 73/4885
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME ARNT, AHR, DRD1 LMNA 4737/4885KMT2A 2412/4885ALDH1A1 73/4885
US-20210280800-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, AOX1, CYBA LMNA 3679/4885KMT2A 1797/4885ALDH1A1 10/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 LMNA 3716/4885KMT2A 2084/4885ALDH1A1 7/4885
US-20210388001-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, TRPC1, TRPA1 LMNA 2887/4885KMT2A 1643/4885ALDH1A1 97/4885
US-20210320260-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, TRPC1 LMNA 2278/4885KMT2A 1491/4885ALDH1A1 78/4885
US-20210184131-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, CYP1A1 LMNA 4099/4885KMT2A 2232/4885ALDH1A1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.