Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218960 | 0.83 | CYP2D6 (0.54) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL2739070 | 0.77 | MGLL (0.48) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL13575585 | 0.75 | TP53 (0.48) | KMT2AGAAMEN1 | |
| SCHEMBL8928315 | 0.75 | TP53 (0.48) | KMT2AGAAMEN1 | |
| SCHEMBL2739068 | 0.75 | KMT2A (0.53) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL219220 | 0.74 | KMT2A (0.56) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL217564 | 0.74 | ALDH1A1 (0.46) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL28130552 | 0.73 | OPRM1 (0.58) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL3919536 | 0.73 | OPRM1 (0.78) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL8175607 | 0.73 | OPRM1 (0.78) | OPRM1CHRM2CHRM4CHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |