Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19487320 | 0.91 | SLC6A4 (0.33) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL17031845 | 0.87 | CHRNA1 (0.33) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL19478834 | 0.79 | SLC6A4 (0.36) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL17033302 | 0.77 | CHRNA1 (0.36) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL18898952 | 0.75 | DRD2 (0.35) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL17050360 | 0.74 | CA2 (0.38) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL20992182 | 0.74 | CHRNA1 (0.36) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL2351449 | 0.73 | CHRNA1 (0.35) | SLC6A4CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL20671092 | 0.73 | ADRA1D (0.41) | — | |
| SCHEMBL19234729 | 0.69 | CA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062790-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062790-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | TFPI, CFD, F3 | SLC6A4 3876/4885CHRNA1 3525/4885CHRNG 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.