Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26137530 | 0.78 | CYP1A2 (0.47) | SLC6A4SLC6A2SLC6A3GSRKDM4E | |
| SCHEMBL21756915 | 0.78 | GABRA1 (0.42) | SLC6A4SLC6A2GABRA1GABRB1GABRB2 | |
| SCHEMBL21756918 | 0.78 | GABRA1 (0.38) | SLC6A4SLC6A2GABRA1GABRB1GABRB2 | |
| SCHEMBL16477897 | 0.77 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3GSRKDM4E | |
| SCHEMBL21756917 | 0.76 | GABRA1 (0.35) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL21756948 | 0.76 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3GABRA1GABRB1 | |
| SCHEMBL681660 | 0.74 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3GSRKDM4E | |
| SCHEMBL21756916 | 0.72 | GABRA1 (0.39) | SLC6A2ALDH1A1GABRA1GABRB1GABRB2 | |
| SCHEMBL12197671 | 0.72 | GABRA1 (0.52) | SLC6A2GABRA1GABRB1GABRB2CYP1A2 | |
| SCHEMBL22864658 | 0.71 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |