Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756918 | 0.80 | GABRA1 (0.38) | GABRA1GABRB1GABRB2SLC6A4SLC6A2 | |
| SCHEMBL21756923 | 0.78 | SLC6A4 (0.46) | GABRA1GABRB1GABRB2SLC6A4SLC6A2 | |
| SCHEMBL15801260 | 0.78 | ACE2 (0.42) | GABRA1GABRB1GABRB2ACE2GABRG2 | |
| SCHEMBL11994518 | 0.78 | TRPA1 (0.55) | GABRA1ACE2GABRG2GABRB3SLC6A2 | |
| SCHEMBL607135 | 0.78 | ACE2 (0.42) | GABRA1GABRB2ACE2GABRG2GABRB3 | |
| SCHEMBL21756948 | 0.77 | SLC6A2 (0.38) | GABRA1GABRB1GABRB2SLC6A4SLC6A2 | |
| SCHEMBL21756917 | 0.77 | GABRA1 (0.35) | GABRA1GABRB1GABRB2 | |
| SCHEMBL11994359 | 0.76 | ACE2 (0.41) | GABRA1ACE2GABRG2GABRB3SLC6A2 | |
| SCHEMBL10053114 | 0.76 | LMNA (0.42) | GABRA1GABRB1ACE2GABRG2GABRB3 | |
| SCHEMBL16959297 | 0.76 | GABRA1 (0.42) | GABRA1GABRB1ACE2GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |