Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.51 |
| ▸ | WNT3A | P56704 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050738 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL2216212 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL137872 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL22721189 | 0.79 | ALDH1A1 (0.83) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL23981733 | 0.79 | MAOA (0.46) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL6197414 | 0.77 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL3224084 | 0.77 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL6423116 | 0.77 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL8521100 | 0.77 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL960143 | 0.76 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |