Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329501 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL21758874 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL27846083 | 0.78 | KMT2A (0.44) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL2216212 | 0.77 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL711360 | 0.77 | RAB9A (0.75) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3414708 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL23855456 | 0.75 | — | — | |
| SCHEMBL22733861 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3237221 | 0.74 | — | — | |
| SCHEMBL22721189 | 0.74 | ALDH1A1 (0.83) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358343-B1 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO KGAA (DE) | 2016-10-19 | — | — | EP | claimed |
| CN-102643879-B | Method for preparing duloxetine chiral intermediate through microbial conversion | ZHEJIANG JIUZHOU PHARM CO LTD | 2015-02-11 | — | — | CN | claimed |
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | claimed |
| CN-102643879-A | Method for preparing duloxetine chiral intermediate through microbial conversion | ZHEJIANG JIUZHOU PHARM CO LTD | 2012-08-22 | — | — | CN | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| CN-102199637-A | Method for preparing (S)-3-hydroxyl-3-(2-thienyl)-propionitrile by microbial transformation | UNIV ZHEJIANG TECHNOLOGY | 2011-09-28 | — | — | CN | claimed |
| EP-2358343-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | Henkel AG & Co. KGaA (DE) | 2011-08-24 | — | — | EP | claimed |
| WO-2010072512-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO. KGAA (DE) | 2010-07-01 | — | — | WO | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| EP-2014275-A2 | Kit for preparing storage-stable formulations | Henkel AG & Co. KGaA (DE) | 2009-01-14 | — | — | EP | claimed |
| WO-2007073922-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2007-07-05 | — | — | WO | claimed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | claimed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | claimed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | claimed |
| US-4716237-A | Process for the production of 3-oxonitriles | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | claimed |
| US-4390545-A | FENBUFEN AND B-OXO (OR) IMINO THIOPHENEPROPIONITRILES | AMERICAN CYANAMID COMPANY (US) | 1983-06-28 | — | — | US | claimed |
| US-4189497-A | B-OXO-2-THIOPHENEPROPIONITRILE | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | ALDH1A1 195/4885LMNA 2210/4885MEN1 4409/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | ALDH1A1 77/4885LMNA 1020/4885MEN1 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.