Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | GSK3B | P49841 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.56 |
| ▸ | WNT3A | P56704 | 4/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209532 | 0.89 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL2216212 | 0.87 | ALDH1A1 (1.00) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL4852587 | 0.87 | HPGD (0.70) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL22721189 | 0.83 | ALDH1A1 (0.83) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL230036 | 0.83 | — | — | |
| SCHEMBL6197414 | 0.82 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL3224084 | 0.82 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL6423116 | 0.82 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL8521100 | 0.82 | ALDH1A1 (0.80) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL10352206 | 0.80 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562253-B1 | MODIFIED CARBONYL REDUCTASE, GENE THEREOF, AND METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THESE | KANEKA CORP (JP) | 2017-08-02 | — | — | EP | claimed |
| US-8658400-B2 | Biocatalysts for manufacturing duloxetine alcohol | BASF SE (DE) | 2014-02-25 | — | — | US | claimed |
| EP-2562253-A1 | MODIFIED CARBONYL REDUCTASE, GENE THEREOF, AND METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THESE | Kaneka Corporation (JP) | 2013-02-27 | — | — | EP | claimed |
| US-20110250655-A1 | Biocatalysts For Manufacturing Duloxetine Alcohol | BASF SE (DE) | 2011-10-13 | — | — | US | claimed |
| EP-1670779-B1 | METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL | BASF SE (DE) | 2010-11-24 | — | — | EP | claimed |
| US-7790436-B2 | Method for production of (1S)-3-chloro-1-(2-thienyl)-propan-1-ol using alcohol dehydrogenase from thermoanaerobacter | BASF SE (DE) | 2010-09-07 | — | — | US | claimed |
| EP-1969133-B1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE (1S)-3-CHLORO-1-(2-THIENYL)-PROPAN-1-OL | BASF SE (DE) | 2010-09-01 | — | — | EP | claimed |
| US-7498448-B2 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-03 | — | — | US | claimed |
| US-20080319208-A1 | Method for Production of Optically Active (1S)-3-Chloro-1-(2-Thienyl)-Propan-1-Ol | BASF SE (DE) | 2008-12-25 | — | — | US | claimed |
| EP-1969133-A1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE (1S)-3-CHLORO-1-(2-THIENYL)-PROPAN-1-OL | BASF SE (DE) | 2008-09-17 | — | — | EP | claimed |
| US-7365212-B2 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | ZACH SYSTEM S.P.A. (IT) | 2008-04-29 | — | — | US | claimed |
| EP-1673375-B1 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG SIPSY (FR) | 2007-08-01 | — | — | EP | claimed |
| WO-2007074060-A1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE (1S)-3-CHLORO-1-(2-THIENYL)-PROPAN-1-OL | BASF SE (DE) | 2007-07-05 | — | — | WO | claimed |
| US-20070083055-A1 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-12 | — | — | US | claimed |
| US-20070055068-A1 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | PPG-SIPSY (FR) | 2007-03-08 | — | — | US | claimed |
| EP-1670779-A2 | METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL | BASF Aktiengesellschaft (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005033094-A2 | METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-14 | — | — | WO | claimed |
| CN-114763317-A | Process for producing alcohol compound | 财团法人工业技术研究院 | 2022-07-19 | — | — | CN | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |
| EP-0339599-A2 | Process for producing acylaromatic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055068-A1 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | OGFR, OXSR1, OTC | ALDH1A1 280/4885LMNA 603/4885KMT2A 1857/4885 |
| US-20070083055-A1 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | RNGTT, TALDO1, DERA | ALDH1A1 369/4885LMNA 2202/4885KMT2A 1053/4885 |
| US-20110250655-A1 | Biocatalysts For Manufacturing Duloxetine Alcohol | ADH5, ADH1A, ADH1C | ALDH1A1 24/4885LMNA 3016/4885KMT2A 1283/4885 |
| US-20080319208-A1 | Method for Production of Optically Active (1S)-3-Chloro-1-(2-Thienyl)-Propan-1-Ol | ADH1A, ADH1C, ADH5 | ALDH1A1 4/4885LMNA 3491/4885KMT2A 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.