Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487745 | 1.00 | ADRA2A (0.44) | ADRA2APNMTADRA2BADRA2CHRH3 | |
| SCHEMBL981053 | 0.88 | ADRA2A (0.52) | ADRA2APNMTADRA2BADRA2CMAPT | |
| SCHEMBL30584650 | 0.88 | ADRA2A (0.52) | ADRA2APNMTADRA2BADRA2CMAPT | |
| SCHEMBL566283 | 0.84 | MAPT (0.54) | ADRA2APNMTADRA2BADRA2CHRH3 | |
| Acetaldehyde SCHEMBL27764807 | 0.78 | ADRA2A (0.43) | ADRA2APNMTADRA2BADRA2CMAPT | |
| SCHEMBL596333 | 0.76 | PNMT (0.48) | ADRA2APNMTADRA2BADRA2CHRH3 | |
| SCHEMBL3873031 | 0.76 | HTR2A (0.47) | ADRA2APNMTADRA2BADRA2CHRH3 | |
| SCHEMBL15320816 | 0.76 | MAPT (0.46) | HRH3MAPTKDM4ECA12CA1 | |
| SCHEMBL3111834 | 0.76 | MAPT (0.50) | HRH3MAPTKDM4ECA12CA1 | |
| SCHEMBL12821127 | 0.76 | HRH3 (0.42) | HRH3MAPTKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-24 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-112804982-B | Near infrared nerve-retaining benzo [ c ] phenoxazine fluorophores | 俄勒冈健康与科学大学 | 2023-07-25 | — | — | CN | disclosed |
| US-20230210854-A1 | MONO- AND COMBINATION THERAPIES | RECURIUM IP HOLDINGS, LLC | 2023-07-06 | — | — | US | disclosed |
| EP-3807274-B1 | 4-SUBSTITUTED PYRROLO[2,3-B]PYRIDINE AS ERBB MODULATORS USEFUL FOR TREATING CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2022-07-27 | — | — | EP | disclosed |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-10 | — | — | US | disclosed |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-10 | — | — | US | disclosed |
| CN-112804982-A | Benzo [ c ] phenoxazine fluorophores for near-infrared nerve retention | 俄勒冈健康与科学大学 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020056046-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-03-19 | — | — | WO | disclosed |
| WO-2020039060-A1 | 4-SUBSTITUTED PYRROLO[2,3-B]PYRIDINE AS ERBB MODULATORS USEFUL FOR TREATING CANCER | LEAD DISCOVERY CENTER GMBH (DE) | 2020-02-27 | — | — | WO | disclosed |
| EP-3613738-A1 | 4-SUBSTITUTED PYRROLO[2,3-B]PYRIDINE AS ERBB MODULATORS USEFUL FOR TREATING CANCER | Lead Discovery Center GmbH (DE) | 2020-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | ADRA2A 668/4885PNMT 193/4885ADRA2B 461/4885 |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | NTRK1, PMP22, PAX3 | ADRA2A 668/4885PNMT 193/4885ADRA2B 461/4885 |
| US-20230210854-A1 | MONO- AND COMBINATION THERAPIES | TP53, BRCA1, MCL1 | ADRA2A 2826/4885PNMT 1888/4885ADRA2B 2503/4885 |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | ADRA2A 668/4885PNMT 193/4885ADRA2B 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.