Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 5/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.35 |
| ▸ | TDP2 | O95551 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584650 | 1.00 | ADRA2A (0.52) | ADRA2APNMTADRA2BADRA2CDRD2 | |
| Acetaldehyde SCHEMBL27764807 | 0.89 | ADRA2A (0.43) | ADRA2APNMTADRA2BADRA2CDRD2 | |
| SCHEMBL30487745 | 0.88 | ADRA2A (0.44) | ADRA2APNMTADRA2BADRA2CGFER | |
| SCHEMBL21760177 | 0.88 | ADRA2A (0.44) | ADRA2APNMTADRA2BADRA2CGFER | |
| SCHEMBL177194 | 0.83 | DRD2 (0.59) | ADRA2APNMTADRA2BADRA2CDRD2 | |
| SCHEMBL21760178 | 0.75 | KDM4E (0.48) | ADRA2APNMTADRA2BADRA2CDRD2 | |
| SCHEMBL33917 | 0.74 | DRD2 (0.70) | DRD2DRD4GFERSMN1; SMN2PARP1 | |
| SCHEMBL426519 | 0.74 | PARP10 (0.56) | DRD2DRD4GFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL5538290 | 0.74 | DRD2 (0.44) | DRD2DRD4GFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL1612916 | 0.74 | PNMT (0.57) | ADRA2APNMTADRA2BADRA2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| EP-4536363-A1 | SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | Nikang Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119790053-A | Sulfonamide derivatives as cyclin dependent kinase 2 inhibitors | 霖康疗法公司 | 2025-04-08 | — | — | CN | disclosed |
| EP-4479406-A1 | OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS | Promega Corporation (US) | 2024-12-25 | — | — | EP | disclosed |
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-24 | — | — | US | disclosed |
| CN-118791417-A | Pink back pteridonic acid derivative, preparation method and application thereof | 安徽工业大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-118359634-A | Pyrazole derivative and medical use thereof | 正大天晴药业集团股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-5972951-A | Tetracyclic spiro compounds, process for their preparation and their use as 5HT1D receptor antagonists | SMITHKLINE BEECHAM PLC (GB) | 1999-10-26 | — | — | US | disclosed |
| WO-1999002502-A2 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 1999-01-21 | — | — | WO | disclosed |
| US-5746776-A | Dry-cleaning kit for in-dryer use | CREATIVE PRODUCTS RESOURCE, INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5736534-A | HYPERPROLIFERATIVE DISEASES; INHIBITORS OF PROTEIN-TYROSINE KINASES SUCH AS EPIDERMAL GROWTH FACTOR RECEPTOR; BRAIN, LUNG, BREAST CANCER; PSORIASIS AND BENIGN PROSTATE HYPERPLASIA | PFIZER INC. (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0799226-A1 | TETRACYCLIC SPIRO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0746554-A1 | 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | PFIZER INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| CN-1032202-C | 6-substituted-hexahydrobenz (cd) indoles and process for preparation therefor | LILLY CO ELI (US) | 1996-07-03 | — | — | CN | disclosed |
| WO-1996019477-A1 | TETRACYCLIC SPIRO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS 5HT1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |
| WO-1995023141-A1 | 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | PFIZER INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| CN-1054419-A | 6-replacement-hexahydro-benzo [CD] indoles and preparation method thereof | LILLY CO ELI (US) | 1991-09-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | ADRA2A 668/4885PNMT 193/4885ADRA2B 461/4885 |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | ADRA2A 2023/4885PNMT 1554/4885ADRA2B 2080/4885 |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | NTRK1, PMP22, PAX3 | ADRA2A 668/4885PNMT 193/4885ADRA2B 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.