Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410369 | 1.00 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1BRD4CTSLCTSS | |
| SCHEMBL3637450 | 0.95 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1BRD4CTSLCTSS | |
| SCHEMBL2195060 | 0.89 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1CTSLCTSSCTSK | |
| SCHEMBL2195057 | 0.89 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1CTSLCTSSCTSK | |
| SCHEMBL2875807 | 0.86 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1BRD4HTTMAPK1 | |
| SCHEMBL21760794 | 0.83 | TP53 (0.55) | BRD4CTSLCTSSCTSKCTSB | |
| SCHEMBL4618795 | 0.83 | GSTO1 (0.52) | L3MBTL1ALDH1A1BRD4CTSLCTSS | |
| SCHEMBL23585396 | 0.80 | CTSL (0.48) | L3MBTL1ALDH1A1CTSLCTSSCTSK | |
| SCHEMBL21760617 | 0.80 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1BRD4TP53SMN1; SMN2 | |
| SCHEMBL21761108 | 0.80 | CTSL (0.48) | L3MBTL1ALDH1A1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |