Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21761804 | 0.93 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2HTR3A | |
| SCHEMBL18163967 | 0.87 | CHKA (0.53) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL12062696 | 0.86 | HPGD (0.47) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8290039 | 0.81 | CHKA (0.50) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL16001231 | 0.78 | SIRT6 (0.55) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL24518338 | 0.78 | CHKA (0.62) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL5203985 | 0.77 | GAA (0.61) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL8320347 | 0.77 | ADRB1 (0.63) | KDM4ENPC1RAB9ASMN1; SMN2HTR3A | |
| SCHEMBL82022 | 0.75 | CHKA (0.64) | CHKANCF1LMNAKDM4ENPC1 | |
| SCHEMBL21761909 | 0.75 | MAPT (0.53) | LMNAKDM4ESMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |