Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607930 | 0.78 | HRH3 (0.54) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL12632249 | 0.77 | LSS (0.49) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL26345944 | 0.76 | HRH3 (0.52) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL659509 | 0.73 | HRH3 (0.82) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL22651931 | 0.73 | HRH3 (0.48) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL610268 | 0.73 | ALDH1A1 (0.59) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL11878418 | 0.72 | NR1H4 (0.50) | ALDH1A1TSHRLMNAGAA | |
| SCHEMBL3674783 | 0.72 | LSS (0.48) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL25137173 | 0.71 | HRH3 (0.56) | HRH3ALDH1A1TSHRTAAR1LSS | |
| SCHEMBL25910281 | 0.70 | HRH3 (0.45) | HRH3ALDH1A1TSHRTAAR1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11147889-B2 | Albumin-binding PSMA inhibitors | CANCER TARGETED TECHNOLOGY LLC (US) | 2021-10-19 | — | — | US | disclosed |
| US-20200061218-A1 | Albumin-Binding PSMA Inhibitors | CANCER TARGETED TECHNOLOGY LLC | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11147889-B2 | Albumin-binding PSMA inhibitors | PSMA1, ALB, PSMA2 | HRH3 3176/4885ALDH1A1 294/4885TSHR 3558/4885 |
| US-20200061218-A1 | Albumin-Binding PSMA Inhibitors | PSMA1, ALB, PSMA2 | HRH3 3176/4885ALDH1A1 294/4885TSHR 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.