Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632249 | 0.87 | LSS (0.49) | LSSHRH3HDAC3HDAC6MCHR1 | |
| SCHEMBL4422777 | 0.84 | RXRA (0.46) | HDAC3HDAC6ALDH1A1PYCR1POLB | |
| SCHEMBL3671007 | 0.82 | SIGMAR1 (0.44) | PYCR1SMN1; SMN2 | |
| SCHEMBL3687860 | 0.80 | PLK1 (0.41) | ALDH1A1HDAC1 | |
| SCHEMBL153898 | 0.80 | KMT2A (0.56) | HDAC6ALDH1A1HDAC1LMNA | |
| SCHEMBL3672078 | 0.80 | ACHE (0.44) | HRH3HDAC3HDAC6ALDH1A1TSHR | |
| SCHEMBL11298330 | 0.79 | CA2 (0.46) | ALDH1A1TSHRSMN1; SMN2HDAC1LMNA | |
| SCHEMBL3671777 | 0.79 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTGAA | |
| SCHEMBL3971183 | 0.79 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL480503 | 0.79 | EPHX2 (0.49) | HDAC6ALDH1A1TSHRSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |