SCHEMBL21764582

SCHEMBL21764582

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nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10160976 0.79 PEPD (0.33)
SCHEMBL159950 0.79 ALDH1A1 (0.39) LMNA
SCHEMBL243552 0.79 LMNA (0.40) LMNA
SCHEMBL31620622 0.79 ALDH1A1 (0.39) LMNA
SCHEMBL14353701 0.78 ALDH1A1 (0.30)
Water SCHEMBL8537661 0.76 ALDH1A1 (0.37) LMNA
SCHEMBL3026098 0.76 CA4 (0.41) LMNA
Ammonia Solution, Strong SCHEMBL11346530 0.76 ALDH1A1 (0.37) LMNA
SCHEMBL695544 0.76 LMNA (0.38) LMNA
Ammonia Solution, Strong SCHEMBL10598799 0.76 ALDH1A1 (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371517-A1 COMBINATIONS TREATMENTS AEQUOR, INC. (US) 2023-11-23 US disclosed
US-20230371517-A1 COMBINATIONS TREATMENTS AEQUOR, INC. (US) 2023-11-23 US disclosed
US-20200060280-A1 Antimicrobial Compounds and Methods of Use AEQUOR, INC. 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200060280-A1 Antimicrobial Compounds and Methods of Use DDT, PFAS, DSTN LMNA 4792/4885
US-20230371517-A1 COMBINATIONS TREATMENTS DDT, AS3MT, GPX4 LMNA 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.