Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.44 |
| ▸ | ITGAV | P06756 | 11/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147868 | 0.90 | ITGB3 (0.47) | ITGB3ITGAVPPARGPPARAPPARD | |
| SCHEMBL3147855 | 0.90 | ITGB3 (0.47) | ITGB3ITGAVPPARGPPARAPPARD | |
| SCHEMBL2174159 | 0.86 | MGLL (0.43) | ITGB3ITGAVPPARGPPARACYP17A1 | |
| SCHEMBL2177181 | 0.85 | MGLL (0.50) | ITGB3ITGAVPPARGPPARAHDAC1 | |
| SCHEMBL12406885 | 0.85 | MGLL (0.50) | ITGB3ITGAVPPARGPPARAHDAC1 | |
| SCHEMBL12406884 | 0.81 | CYP17A1 (0.44) | ITGB3ITGAVCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1749498 | 0.77 | CYP11B1 (0.41) | PPARGPPARAPPARDCYP11B1CYP11B2 | |
| SCHEMBL7815559 | 0.76 | ESR1 (0.55) | PPARA | |
| SCHEMBL3187411 | 0.76 | PPARG (0.52) | ITGB3ITGAVPPARGPPARAPPARD | |
| SCHEMBL3187393 | 0.76 | PPARG (0.52) | ITGB3ITGAVPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |