Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.39 |
| ▸ | ITGAV | P06756 | 8/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146484 | 0.90 | SRR (0.44) | MGLLITGB3ITGAVALBITGA2B | |
| SCHEMBL3146470 | 0.90 | SRR (0.44) | MGLLITGB3ITGAVALBITGA2B | |
| SCHEMBL2176552 | 0.86 | ITGB3 (0.44) | MGLLITGB3ITGAVCYP17A1CYP11B1 | |
| SCHEMBL12406885 | 0.83 | MGLL (0.50) | MGLLITGB3ITGAVHDAC1HDAC6 | |
| SCHEMBL2177181 | 0.83 | MGLL (0.50) | MGLLITGB3ITGAVHDAC1HDAC6 | |
| SCHEMBL12406884 | 0.78 | CYP17A1 (0.44) | MGLLITGB3ITGAVCYP17A1CYP11B1 | |
| SCHEMBL2173501 | 0.77 | HDAC1 (0.43) | HDAC1HDAC6PPARGPPARA | |
| SCHEMBL2173508 | 0.77 | HDAC1 (0.43) | HDAC1HDAC6PPARGPPARA | |
| SCHEMBL2176885 | 0.76 | PLG (0.40) | ITGB3ITGAV | |
| SCHEMBL2176888 | 0.76 | PLG (0.40) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |
| EP-1742608-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϝ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005108352-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϜ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-11-17 | — | — | WO | disclosed |