Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12406885 | 1.00 | MGLL (0.50) | MGLLENPP2ITGB3ITGAVPPARG | |
| SCHEMBL3187411 | 0.91 | PPARG (0.52) | MGLLENPP2ITGB3ITGAVPPARG | |
| SCHEMBL3187393 | 0.91 | PPARG (0.52) | MGLLENPP2ITGB3ITGAVPPARG | |
| SCHEMBL2176552 | 0.85 | ITGB3 (0.44) | MGLLITGB3ITGAVPPARGPPARA | |
| SCHEMBL2174159 | 0.83 | MGLL (0.43) | MGLLITGB3ITGAVPPARGPPARA | |
| SCHEMBL28851015 | 0.82 | PSMB5 (0.54) | PPARGPPARASRR | |
| SCHEMBL28851016 | 0.82 | PSMB5 (0.54) | PPARGPPARASRR | |
| SCHEMBL12406884 | 0.80 | CYP17A1 (0.44) | MGLLENPP2ITGB3ITGAVHDAC1 | |
| SCHEMBL3147855 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVPPARGPPARASRR | |
| SCHEMBL3147868 | 0.77 | ITGB3 (0.47) | ITGB3ITGAVPPARGPPARASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |