Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31606582 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL6779193 | 0.85 | TSHR (0.43) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL3989842 | 0.82 | HDAC6 (0.40) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL31541270 | 0.81 | GABRP (0.52) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL7819216 | 0.81 | KMT2A (0.55) | ALDH1A1TSHRGAAMAPTKMT2A | |
| SCHEMBL2189058 | 0.81 | KMT2A (0.59) | ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL21765852 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL9369081 | 0.80 | KMT2A (0.54) | ALDH1A1TSHRGAAMAPTKMT2A | |
| SCHEMBL21765667 | 0.77 | KMT2A (0.46) | ALDH1A1MAPTSMN1; SMN2KMT2APOLB | |
| SCHEMBL31541242 | 0.77 | CDC25B (0.50) | ALDH1A1TSHRTP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |