Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765870 | 0.92 | TSPO (0.49) | ALDH1A1TSHRMAPTTP53GAA | |
| SCHEMBL4781144 | 0.88 | CYP3A4 (0.46) | ALDH1A1TSHRMAPTTP53KDM4E | |
| SCHEMBL21765851 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPTTP53GAA | |
| SCHEMBL13684202 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTTP53GAA | |
| SCHEMBL13041531 | 0.85 | POLB (0.51) | ALDH1A1TSHRMAPTTP53GAA | |
| SCHEMBL8720338 | 0.83 | TACR1 (0.57) | ALDH1A1TSHRMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13007694 | 0.83 | SIGMAR1 (0.61) | ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6529361 | 0.83 | ESR1 (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL13041529 | 0.82 | POLQ (0.50) | ALDH1A1GAANPC1RAB9AKDM4E | |
| SCHEMBL13041521 | 0.80 | KMT2A (0.56) | ALDH1A1TSHRMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |