Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802255 | 0.90 | NPC1 (0.45) | NPC1MEN1KMT2ATPSAB1PTPN1 | |
| SCHEMBL3742024 | 0.88 | PTPN1 (0.54) | NPC1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL15267699 | 0.84 | KMT2A (0.60) | NPC1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL4787002 | 0.81 | KMT2A (0.51) | NPC1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL8667875 | 0.81 | KMT2A (0.48) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL32665587 | 0.81 | TRPV1 (0.54) | MEN1KMT2ATPSAB1PTPN1PRSS1 | |
| SCHEMBL28822072 | 0.81 | L3MBTL1 (0.64) | MEN1KMT2ATPSAB1PRSS1GAA | |
| SCHEMBL23565002 | 0.79 | KMT2A (0.66) | NPC1MEN1KMT2AGAARAB9A | |
| SCHEMBL20740269 | 0.79 | LMNA (0.68) | KMT2ARAB9APOLBLMNA | |
| SCHEMBL23564742 | 0.79 | KMT2A (0.65) | NPC1MEN1KMT2ARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |