Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412289 | 0.92 | CYP3A4 (0.48) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL21765866 | 0.71 | JAK3 (0.35) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL13002983 | 0.69 | GAA (0.63) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4413676 | 0.69 | MAPT (0.44) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL2661353 | 0.68 | PKM (0.67) | CYP3A4ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL9954231 | 0.68 | HRH2 (0.43) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4412558 | 0.68 | SMN1; SMN2 (0.46) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL13989319 | 0.68 | GAA (0.73) | CYP3A4ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4410319 | 0.67 | DRD2 (0.49) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL34461886 | 0.67 | DRD2 (0.49) | ALDH1A1KDM4EHPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |