SCHEMBL4412558

SCHEMBL4412558

CC(=O)Nc1ccc(NC(C)=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.46
HSD17B10 Q99714 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
ALOX15 P16050 1/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
PTK2 Q05397 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA12 O43570 1/20 0.44
BRD4 O60885 1/20 0.44
NR1I2 O75469 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MB P02144 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358942 0.81 RXFP1 (0.43) SMN1; SMN2HSD17B10GAAPKMALOX15
SCHEMBL3797719 0.80 KDM4E (0.37) SMN1; SMN2HSD17B10GAAPKMALOX15
SCHEMBL13135968 0.78 HSD17B10 (0.42) HSD17B10GAANAPRTALDH1A1MAPT
SCHEMBL655272 0.75 KCNH2 (0.51) GAAPTK2KMT2AMEN1MAPT
SCHEMBL1827087 0.74 KCNH2 (0.50) GAAPTK2KMT2AMEN1MAPT
SCHEMBL4412289 0.73 CYP3A4 (0.48) SMN1; SMN2GAAPKMALDH1A1KMT2A
SCHEMBL4419122 0.72
SCHEMBL6689158 0.70 ALDH1A1 (0.74) SMN1; SMN2HSD17B10HTTNAPRTALDH1A1
SCHEMBL8425277 0.70
SCHEMBL3451050 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9703008-B2 Optical film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-07-11 US disclosed
US-20150355491-A1 OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-10 US disclosed
US-20150355397-A1 OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-10 US disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed