Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037168 | 0.84 | LMNA (0.42) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL21766165 | 0.83 | RAB9A (0.44) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL5034142 | 0.80 | NOD2 (0.48) | NOD2NOD1L3MBTL1KMT2ACA9 | |
| SCHEMBL6422004 | 0.80 | NOD2 (0.53) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL2729849 | 0.76 | RAB9A (0.51) | RAB9ALMNAKDM4EKMT2ACA12 | |
| SCHEMBL2497241 | 0.75 | LMNA (0.45) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL15604817 | 0.75 | CA12 (0.42) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL6022038 | 0.74 | TSHR (0.44) | NOD2NOD1LMNAKDM4ETSHR | |
| SCHEMBL23679186 | 0.71 | ALDH1A1 (0.47) | RAB9ANOD2NOD1LMNAKDM4E | |
| SCHEMBL10004099 | 0.69 | NOD2 (0.54) | NOD2NOD1LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038456-A1 | CRYSTAL FORM OF TRI-CYCLE COMPOUND AND APPLICATION THEREOF | 福建广生堂药业股份有限公司 | 2020-02-27 | — | — | WO | disclosed |