Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21118783 | 0.85 | MMP1 (0.40) | EPHX1ZDHHC20ZDHHC2PLA2G2APLA2G4A | |
| SCHEMBL545376 | 0.84 | EPHX1 (0.57) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL26598585 | 0.84 | EPHX1 (0.57) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL7161002 | 0.82 | PLA2G2A (0.59) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL14138655 | 0.82 | CASP2 (0.60) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL6280150 | 0.82 | NAAA (0.56) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL11234065 | 0.81 | PLA2G2A (0.57) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL11234059 | 0.81 | CASP2 (0.58) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL15104604 | 0.81 | PLA2G2A (0.57) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A | |
| SCHEMBL15104686 | 0.81 | PLA2G2A (0.57) | EPHX1ZDHHC20ZDHHC2NAAAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3024460-B1 | METHOD FOR PRODUCING ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER | IMMUNOMEDICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3613792-A1 | MULTI-ARM TARGETED ANTI-CANCER CONJUGATE | Bright Gene Bio-Medical Technology Co., Ltd. (CN) | 2020-02-26 | — | — | EP | disclosed |