Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180161 | 0.76 | NAMPT (0.37) | NAMPTTDP1 | |
| SCHEMBL2197922 | 0.76 | GCK (0.50) | NAMPTGCK | |
| SCHEMBL2038418 | 0.74 | KMT2A (0.38) | NAMPTGCK | |
| SCHEMBL2178622 | 0.64 | NAMPT (0.34) | NAMPTGCK | |
| SCHEMBL1959747 | 0.63 | GCK (0.58) | GCK | |
| SCHEMBL1959745 | 0.63 | GCK (0.58) | GCK | |
| SCHEMBL22399279 | 0.62 | NAMPT (0.68) | NAMPT | |
| SCHEMBL3350798 | 0.62 | MAPT (0.72) | TDP1 | |
| SCHEMBL29098532 | 0.61 | ALDH1A1 (0.72) | — | |
| SCHEMBL22399268 | 0.60 | NAMPT (0.57) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |