Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179599 | 0.82 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL2177327 | 0.78 | RXRA (0.33) | — | |
| SCHEMBL2177887 | 0.73 | CYP11B1 (0.39) | TUBB1 | |
| SCHEMBL2177830 | 0.72 | ALDH1A1 (0.38) | TUBB1 | |
| SCHEMBL2177631 | 0.72 | — | — | |
| SCHEMBL2177635 | 0.72 | — | — | |
| SCHEMBL2177927 | 0.72 | — | — | |
| SCHEMBL1638390 | 0.72 | PTGS2 (0.54) | PTGS2TUBB1 | |
| SCHEMBL2176878 | 0.71 | — | — | |
| SCHEMBL17007321 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166162-A1 | 1,2-Benzisothiazole Compounds Useful for Combating Animal Pests | GLRX3, CBR3, PRDX1 | PTGS2 3627/4885TUBB1 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.