Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176940 | 0.90 | MAPT (0.43) | ACHEMAPTTP53KMT2AKDM4E | |
| SCHEMBL2178067 | 0.75 | AOC3 (0.43) | MAPTKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2177637 | 0.75 | CASR (0.44) | KMT2AL3MBTL1 | |
| SCHEMBL11618270 | 0.72 | AOC3 (0.51) | ACHECA1CA2CA9L3MBTL1 | |
| SCHEMBL29950797 | 0.72 | MAPT (0.46) | ACHEFFAR4MAPTTP53KMT2A | |
| SCHEMBL2179422 | 0.71 | L3MBTL1 (0.49) | KMT2AKDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2177096 | 0.70 | ALDH1A1 (0.45) | MAPTTP53KMT2AKDM4EMEN1 | |
| SCHEMBL7652207 | 0.69 | KMT2A (0.49) | ACHEKMT2AL3MBTL1CHRM2CHRM1 | |
| SCHEMBL29061992 | 0.69 | KMT2A (0.49) | ACHEKMT2AL3MBTL1CHRM2CHRM1 | |
| SCHEMBL15474102 | 0.69 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |