SCHEMBL21769672

SCHEMBL21769672

COCc1cc(I)ccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
ALDH1A1 P00352 4/20 0.34
PRKCE Q02156 2/20 0.34
MYLK Q15746 2/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
PRKCG P05129 1/20 0.34
PRKCA P17252 1/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTT P42858 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
APP P05067 4/20 0.33
KDM4E B2RXH2 3/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28566402 0.79 IDO1 (0.33) IDO1
SCHEMBL791955 0.78 TAAR1 (0.52) ALDH1A1MEN1KMT2ATDP1HTT
SCHEMBL23072809 0.78 MEN1 (0.35) IDO1ALDH1A1PRKCEMYLKMAPT
SCHEMBL24892983 0.77 HSD17B3 (0.45) ALDH1A1PRKCEMYLKMAPTMEN1
SCHEMBL15121002 0.76 KIF11 (0.36) TAAR1SLC6A4
SCHEMBL27804944 0.76 TAAR1 (0.34) IDO1TAAR1SLC6A2SLC6A4
SCHEMBL4018262 0.75 ALDH1A1 (0.48) ALDH1A1MAPTMEN1RECQLKMT2A
SCHEMBL12094541 0.75 SLC6A4 (0.41) IDO1TDP1SLC6A2SLC6A4
SCHEMBL20633523 0.75 FFAR4 (0.40) ALDH1A1PRKCEMYLKMAPTMEN1
SCHEMBL13703979 0.75 IDO1 (0.47) IDO1TAAR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020039088-A2 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2020-02-27 WO disclosed