Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | MYLK | Q15746 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 5/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31197259 | 0.83 | IDO1 (0.36) | IDO1APP | |
| SCHEMBL21241614 | 0.78 | HSD17B3 (0.44) | MEN1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL5936401 | 0.78 | PTPN1 (0.39) | MEN1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL13178886 | 0.78 | FFAR4 (0.43) | MEN1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL21769672 | 0.78 | IDO1 (0.35) | MEN1ALDH1A1KMT2AHTTIDO1 | |
| SCHEMBL15430107 | 0.77 | GABRA1 (0.39) | ALDH1A1KMT2AHTR2AMAPTSLC6A4 | |
| SCHEMBL19794836 | 0.77 | IDO1 (0.30) | IDO1 | |
| SCHEMBL791872 | 0.76 | IDO1 (0.46) | IDO1HTR2ASLC6A4 | |
| SCHEMBL30910900 | 0.76 | NR3C1 (0.37) | MEN1ALDH1A1KMT2ATSHRHTT | |
| SCHEMBL30945993 | 0.76 | IDO1 (0.46) | IDO1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| EP-3789470-A1 | LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS | Merck Patent GmbH (DE) | 2021-03-10 | — | — | EP | disclosed |