Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769889 | 0.75 | HTT (0.39) | TP53SMN1; SMN2CNR2CNR1HTT | |
| SCHEMBL21769880 | 0.72 | LMNA (0.40) | SMN1; SMN2CNR2CNR1HTTALDH1A1 | |
| SCHEMBL905171 | 0.65 | CNR2 (0.48) | TP53SMN1; SMN2CNR2CNR1ALDH1A1 | |
| SCHEMBL6843778 | 0.63 | MLYCD (0.64) | SMN1; SMN2 | |
| SCHEMBL7141111 | 0.62 | HTT (0.63) | TP53SMN1; SMN2CNR2CNR1HTT | |
| SCHEMBL6521921 | 0.61 | HTR2C (0.43) | CNR2CNR1 | |
| SCHEMBL6843906 | 0.61 | MLYCD (0.61) | SMN1; SMN2 | |
| SCHEMBL5085615 | 0.61 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL2938750 | 0.60 | MLYCD (0.60) | SMN1; SMN2CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL3394146 | 0.60 | HTR2C (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |