Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769873 | 0.87 | — | — | |
| SCHEMBL14000159 | 0.76 | MAPT (0.37) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| Amenamevir SCHEMBL2238614 | 0.75 | HDAC1 (0.37) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14000191 | 0.75 | SLC6A9 (0.43) | — | |
| SCHEMBL2238684 | 0.73 | CHRM1 (0.36) | L3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL2815306 | 0.72 | HTT (0.39) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28459274 | 0.70 | GAA (0.36) | L3MBTL1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2239362 | 0.69 | HDAC1 (0.38) | L3MBTL1 | |
| SCHEMBL21769886 | 0.68 | POLB (0.36) | L3MBTL1MAPTALDH1A1POLBTDP1 | |
| SCHEMBL21769890 | 0.68 | HTT (0.36) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |