Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892475 | 0.85 | TSHR (0.39) | CYP1A2POLBTSHRL3MBTL1KDM4E | |
| SCHEMBL13257188 | 0.74 | POLB (0.43) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21769834 | 0.72 | POLB (0.33) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22993923 | 0.70 | KDM4E (0.39) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1311424 | 0.67 | TSHR (0.35) | TSHR | |
| SCHEMBL8080497 | 0.67 | TSHR (0.35) | TSHRKDM4EALDH1A1GAAF2 | |
| SCHEMBL1562353 | 0.66 | TSHR (0.38) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16768500 | 0.65 | TSHR (0.35) | CYP1A2POLBTSHRL3MBTL1KDM4E | |
| SCHEMBL8534649 | 0.64 | ALDH1A1 (0.48) | POLBTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9687982 | 0.64 | PTPN1 (0.36) | POLBTSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |