Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892475 | 0.71 | TSHR (0.39) | ALDH1A1KDM4EGAASMN1; SMN2HTT | |
| SCHEMBL22993923 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EGAASMN1; SMN2HTT | |
| SCHEMBL22003316 | 0.68 | MAOA (0.41) | ALDH1A1KDM4EMAPTHPGDPOLB | |
| SCHEMBL9419018 | 0.67 | RXFP1 (0.41) | ALDH1A1LMNAPOLBL3MBTL1CES1 | |
| SCHEMBL31196088 | 0.67 | KDM4E (0.36) | ALDH1A1KDM4EGAASMN1; SMN2HTT | |
| SCHEMBL11577071 | 0.67 | MMP2 (0.50) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11660319 | 0.67 | POLB (0.35) | ALDH1A1GAALMNAPOLBL3MBTL1 | |
| SCHEMBL20975606 | 0.66 | NOTUM (0.34) | HTTLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL29223835 | 0.65 | HCAR2 (0.47) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8707641 | 0.65 | HTR1A (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |