Sugi Predict

Sugi Predict / Compounds / SCHEMBL892475

SCHEMBL892475

SCHEMBL892475

CC1(C)OC(=O)C2(CC2)C(=O)O1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ GAA P10253 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ F2 P00734 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ LMNA P02545 3/20 0.35
▸ GLA P06280 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.32
▸ PTPN1 P18031 2/20 0.32
▸ TP53 P04637 2/20 0.30
▸ MAPK1 P28482 2/20 0.30
▸ HIF1A Q16665 2/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21769875 0.85 CYP1A2 (0.38) TSHRPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL13257188 0.82 POLB (0.43) TSHRPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL21769834 0.80 POLB (0.33) TSHRPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL22993923 0.77 KDM4E (0.39) TSHRPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL9687982 0.75 PTPN1 (0.36) TSHRPOLBKDM4ELMNAPTPN1
SCHEMBL8080497 0.74 TSHR (0.35) TSHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL1311424 0.74 TSHR (0.35) TSHRPTPN1
SCHEMBL8782037 0.74 ALDH1A1 (0.42) L3MBTL1KDM4EALDH1A1GAASMN1; SMN2
SCHEMBL1562353 0.73 TSHR (0.38) TSHRPOLBL3MBTL1KDM4EALDH1A1
SCHEMBL16768500 0.72 TSHR (0.35) TSHRPOLBL3MBTL1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800945-A Pyrrolidone-containing 2-phenylpyridine derivative, synthesis method, application and herbicide thereof 贵州大学 2024-04-02 — — CN claimed
JP-1070488-A — — None — — JP disclosed
EP-4306529-B1 FGFR INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS INC (US) 2026-01-21 — — EP disclosed
US-12522605-B2 FGFR inhibitors and methods of use thereof RELAY THERAPEUTICS, INC. (US) 2026-01-13 — — US disclosed
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 — — US disclosed
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 — — US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 — — US disclosed
US-12203938-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2025-01-21 — — US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 — — US disclosed
US-5138057-A CHEMICAL PROCESS FOR THE PREPARATION OF PURINE DERIVATIVES BEECHAM GROUP P.L.C. (GB) 1992-08-11 — — US disclosed
EP-0486807-A1 Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates SYNTEX (U.S.A.) INC. (US) 1992-05-27 — — EP disclosed
US-5082951-A Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates (I) and intermediates therefor SYNTEX (U.S.A.) INC. (US) 1992-01-21 — — US disclosed
US-4988822-A Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates SYNTEX (U.S.A.) INC. (US) 1991-01-29 — — US disclosed
EP-0405506-A1 Tetrapeptide type-B CCK receptor ligands ABBOTT LABORATORIES (US) 1991-01-02 — — EP disclosed
EP-0369583-A1 Chemical process for the preparation of purine derivatives BEECHAM GROUP PLC (GB) 1990-05-23 — — EP disclosed
US-4895956-A ANTIINFLAMMATORY, ANALGESIC HISAMITSU PHARMACEUTICAL CO., LTD. (JP) 1990-01-23 — — US disclosed
US-4873340-A Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates SYNTEX (U.S.A.) INC. (US) 1989-10-10 — — US disclosed
JP-S6470488-A NOVEL 3-AROYL-6,7-DIHYDRO-5H-PYRROLO(1,2-C)IMIDAZOLE-7-CARBOXYLIC ACID DERIVATIVE HISAMITSU PHARMACEUTICAL CO 1989-03-15 — — JP disclosed
EP-0302644-A2 Purine compounds and their preparation BEECHAM GROUP PLC (GB) 1989-02-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12203938-B2 Levetiracetam immunoassays GABRG1, GABRA6, LY96 TSHR 1703/4885POLB 3968/4885L3MBTL1 1773/4885
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT TSHR 4599/4885POLB 2309/4885L3MBTL1 1754/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT TSHR 4599/4885POLB 2309/4885L3MBTL1 1754/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT TSHR 4599/4885POLB 2309/4885L3MBTL1 1754/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT TSHR 4599/4885POLB 2309/4885L3MBTL1 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.