Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26316731 | 0.81 | AURKA (0.54) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL1549465 | 0.79 | GRM2 (0.50) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL21035639 | 0.77 | CYP11B1 (0.54) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL2411349 | 0.77 | CYP11B1 (0.59) | RAB9ANPC1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL28288104 | 0.75 | CCR1 (0.40) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL30888429 | 0.75 | CCR1 (0.40) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL1006499 | 0.75 | SLC6A4 (0.52) | RAB9ANPC1MAPTSLC6A4CYP3A4 | |
| SCHEMBL21769964 | 0.74 | RORC (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL19992711 | 0.74 | APP (0.46) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL389742 | 0.74 | PTGS2 (0.45) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039027-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |