Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363123 | 0.84 | BCL2 (0.44) | IDO1PTGS2FFAR4MEN1KMT2A | |
| SCHEMBL8993689 | 0.83 | PTGS2 (0.50) | MKNK1MKNK2IDO1PTGS2PDCD1 | |
| SCHEMBL29899606 | 0.79 | ENPP2 (0.45) | PRKCIMEN1KMT2AMAPT | |
| SCHEMBL95655 | 0.79 | ENPP2 (0.45) | PRKCIMEN1KMT2AMAPT | |
| SCHEMBL30849630 | 0.78 | IDO1 (0.50) | IDO1KIF11PTGS2MEN1KMT2A | |
| SCHEMBL3480820 | 0.78 | IDO1 (0.50) | IDO1KIF11PTGS2MEN1KMT2A | |
| SCHEMBL12947919 | 0.77 | IDO1 (0.46) | IDO1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL16578698 | 0.77 | PRKCI (0.68) | MKNK1MKNK2PRKCIKIF11MEN1 | |
| SCHEMBL13525205 | 0.76 | HDAC8 (0.50) | MKNK1MKNK2PRKCIKIF11PDCD1 | |
| SCHEMBL970462 | 0.76 | ALDH1A1 (0.48) | IDO1PTGS2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039027-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |