Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 3/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LOX | P28300 | 8/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.52 |
| ▸ | KLK1 | P06870 | 2/20 | 0.51 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891990 | 0.89 | ALDH1A1 (0.52) | PLAUALDH1A1NPC1LMNARAB9A | |
| SCHEMBL22441340 | 0.81 | MEN1 (0.59) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15727556 | 0.81 | LMNA (0.67) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL22457821 | 0.79 | NPC1 (0.57) | ALDH1A1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4163710 | 0.79 | HDAC1 (0.54) | PLAUALDH1A1PLGPLATKLKB1 | |
| SCHEMBL22441225 | 0.78 | RAB9A (0.63) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28200509 | 0.78 | MEN1 (0.74) | PLAUALDH1A1PLGPLATKLKB1 | |
| SCHEMBL24892341 | 0.78 | S1PR1 (0.65) | PLAUPLGKLKB1NPC1RAB9A | |
| SCHEMBL24891739 | 0.77 | PLG (0.64) | PLAUPLGPLATKLKB1PRSS1 | |
| SCHEMBL30182163 | 0.77 | PLG (0.64) | PLAUPLGPLATKLKB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039027-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |