Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21770768 | 0.77 | MCHR1 (0.54) | MCHR1SIGMAR1EBPCYP1A2LTA4H | |
| SCHEMBL25399599 | 0.76 | SIGMAR1 (0.48) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL21770763 | 0.76 | ALK (0.45) | KDM4EALDH1A1HPGDMCHR1SIGMAR1 | |
| SCHEMBL21770766 | 0.74 | SIGMAR1 (0.42) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL492266 | 0.72 | MCHR1 (0.60) | ALDH1A1MCHR1SIGMAR1EBPCYP1A2 | |
| SCHEMBL5856160 | 0.71 | MCHR1 (0.59) | ALDH1A1MCHR1SIGMAR1EBPCYP1A2 | |
| SCHEMBL2079638 | 0.70 | NQO1 (0.43) | KDM4EALDH1A1HTTMAPTKMT2A | |
| SCHEMBL18296421 | 0.70 | DUT (0.36) | — | |
| SCHEMBL11580118 | 0.70 | HTR7 (0.54) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9706125 | 0.68 | EBP (0.72) | MCHR1SIGMAR1EBPCYP1A2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| US-20200062729-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DISCOVERY PURCHASER CORPORATION | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827616-B2 | Heterocyclic compounds as pesticides | DDT, CHRM1, ACHE | KDM4E 1052/4885ALDH1A1 1236/4885HPGD 3410/4885 |
| US-20200062729-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | CHRM1, DDT, ACHE | KDM4E 1061/4885ALDH1A1 1249/4885HPGD 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.