Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178398 | 0.85 | DYRK1A (0.61) | DYRK1AADORA3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9013267 | 0.83 | ABCG2 (0.62) | ADORA3SYKADORA2BCYP1A2ABCG2 | |
| SCHEMBL2176136 | 0.81 | ALDH1A1 (0.51) | DYRK1AADORA3ADORA2BABCG2CLK4 | |
| SCHEMBL26059423 | 0.80 | DYRK1A (0.75) | DYRK1AADORA3SYKADORA2BCYP1A1 | |
| SCHEMBL9013358 | 0.79 | DYRK1A (0.54) | DYRK1ACYP1A1CYP1A2CYP1B1ABCG2 | |
| SCHEMBL15757669 | 0.75 | DYRK1A (0.67) | DYRK1AADORA3SYKADORA2BKDM4E | |
| SCHEMBL28331814 | 0.75 | CLK4 (0.55) | DYRK1ACLK4 | |
| SCHEMBL28233415 | 0.74 | CLK4 (0.67) | DYRK1ASYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2623115 | 0.74 | KDM4E (0.61) | ADORA3CYP1A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL338452 | 0.73 | CLK4 (0.64) | ADORA3SYKCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519501-B1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | UNIV WIEN TECH (AT) | 2015-04-22 | — | — | EP | claimed |
| US-8986994-B2 | Substituted pyridines and pyrimidines | TECHNISCHE UNIVERSITAET WIEN (AT) | 2015-03-24 | — | — | US | claimed |
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2012-11-22 | — | — | US | claimed |
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | claimed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | claimed |
| EP-2519501-B1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | UNIV WIEN TECH (AT) | 2015-04-22 | — | — | EP | disclosed |
| US-8986994-B2 | Substituted pyridines and pyrimidines | TECHNISCHE UNIVERSITAET WIEN (AT) | 2015-03-24 | — | — | US | disclosed |
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | MEDIZINISCHE UNIVERSITAET WIEN (AT) | 2012-11-22 | — | — | US | disclosed |
| EP-2519501-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES FOR THE PRODUCTION OF CARDIOMYOCYTE-LIKE CELLS | Technische Universität Wien (AT) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011079343-A2 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TECHNISCHE UNIVERSITAET WIEN (AT) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294835-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES | TNNI3, TNNT2, PROX1 | DYRK1A 2715/4885ADORA3 972/4885SYK 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.