Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178398 | 0.89 | DYRK1A (0.61) | DYRK1AKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL17720570 | 0.87 | KDM4E (0.57) | DYRK1AKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL26059423 | 0.84 | DYRK1A (0.75) | DYRK1AKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL9013541 | 0.79 | ABCG2 (0.54) | DYRK1AKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL632828 | 0.79 | LMNA (0.64) | DYRK1AKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL2177144 | 0.79 | DYRK1A (0.50) | DYRK1AKDM4EALDH1A1ABCG2CYP1A1 | |
| SCHEMBL28859110 | 0.79 | ADORA2A (0.47) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL13933596 | 0.78 | ADORA2A (0.66) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9013267 | 0.77 | ABCG2 (0.62) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL338452 | 0.77 | CLK4 (0.64) | KDM4ERAB9AALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |