Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.58 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021355 | 0.87 | PTGES (0.43) | PTGESRIPK1KMT2AMEN1LMNA | |
| SCHEMBL7025759 | 0.84 | GRIN2D (0.43) | PTGESKMT2AMEN1LMNARECQL | |
| SCHEMBL6183303 | 0.83 | PTGES (0.62) | PTGESRIPK1PYCR1KMT2AMEN1 | |
| SCHEMBL8154608 | 0.83 | MEN1 (0.42) | KMT2AMEN1HTTLMNARECQL | |
| SCHEMBL6186387 | 0.81 | PTGES (0.59) | PTGESRIPK1PYCR1KMT2AMEN1 | |
| SCHEMBL7024994 | 0.80 | ACHE (0.44) | PTGESLMNATAAR1RECQL | |
| SCHEMBL7025022 | 0.79 | POLB (0.41) | PTGESKMT2ALMNARECQLALDH1A1 | |
| SCHEMBL67173 | 0.79 | RIPK1 (0.56) | PTGESRIPK1PYCR1KMT2AMEN1 | |
| SCHEMBL6032493 | 0.78 | PTGES (0.51) | PTGES | |
| SCHEMBL3571606 | 0.77 | PTGES (0.55) | PTGESRIPK1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |