Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871489 | 0.85 | TAAR1 (0.47) | MEN1KMT2ACTSKMMEPOLB | |
| SCHEMBL2177178 | 0.83 | PTGES (0.58) | MEN1KMT2ALMNAALDH1A1HTT | |
| SCHEMBL17468507 | 0.80 | LMNA (0.44) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7021355 | 0.78 | PTGES (0.43) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL1156558 | 0.76 | PKM (0.38) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL68236 | 0.76 | HSP90AA1 (0.34) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1684422 | 0.75 | MEN1 (0.55) | MEN1KMT2ALMNAALDH1A1MME | |
| SCHEMBL7025759 | 0.74 | GRIN2D (0.43) | MEN1KMT2ALMNAL3MBTL1RECQL | |
| SCHEMBL13900616 | 0.74 | LMNA (0.51) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL15055351 | 0.74 | MEN1 (0.41) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000014109-A1 | BASIC PRODUCTS HAVING ANTAGONISTIC ACTIVITY ON THE NK-1 RECEPTOR AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | MENARINI RICERCHE S.P.A. (IT) | 2000-03-16 | — | — | WO | disclosed |